What is ELiAH?

comprehensive repertoire of E3 ligases for ubiquitination-based TPD drug development including mutually associated target gene, tissue specific expression.

Background of TPD

Recently, TPD (targeted protein degradation) has emerged as promising pharmaceutical approach. Although there are diverse mode of actions in TPD, some of them uses E3 ligase-triggered ubiquitination. This unique mechanism mediates the ubiquitin-proteasome system inherent in the human body as a binder then de$